A Role for Sunlight in Skin Cancer: Research
Sunlight is a carcinogen that everyone is exposed to throughout life. This is considered to be a leading cause of skin cancer. Within the progression of tumor development, those that may be related to sunlight damage would be identified if they contained mutations specific to UV. It was found that 14/24 (58%) Of New England and Swedish patients found the mutation in the p53 tumor suppressor gene. The role of the UV light in the p53 mutations is shown by the double base change in three of the tumors which is known to be induced by UV. These mutations caused by the UV light are substitution mutations which can cause great harm because once it has mutated it replicates as the mutated gene. The squamous cell carcinoma of the skin is an ideal cancer for determining which of the many steps in tumorgenesis is carcinogen related.
The materials and methods used to research this were as such. Patients used for the tests were from the greater......

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Title: Gideon V. Wainwright
Approximate Word Count: 720
Approximate Pages: 3 (250 words per double-spaced page)

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