Abstract

Von Willebrand's Disease is a genetic coagulation disorder that specifically affects the production of the von Willebrand Factor protein. This protein is a vital component for primary Hemostasis and the Coagulation process. Without von Willebrand Factor, or abnormal levels of it, production of other vital proteins will be impeded thus causing the whole process to fail or slow down. The canis domesticus species (dogs) is the animal model of focus for this report. Through studying other animal models, we can become more familiar with the disease as well as note any common links. This will aid in prevention, treatment, and ultimately curing the disease.

Introduction

Erik von Willebrand first described human von Willebrand's disease (vWd) in 1926. About four and a half decades later, in 1970, the first case of canine von Willebrand's disease was described. This first case was seen in the German Shepherd breed. Today many cases of von Willebrand's disease......

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Title: Von Willebrand's Disease In Dogs
Approximate Word Count: 2716
Approximate Pages: 11 (250 words per double-spaced page)

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