The genetic disorder I have looked at in this scientific statement is Tay-Sachs disease or TSD, a serious, inherited fatal brain disorder. The disease is named after Warren Tay, a British ophthalmologist who first described the disease in 1881 and a New York neurologist, Bernard Sachs; who first described the cellular changes and the genetic nature of the disease in 1887.

This rare hereditary disease is caused by a genetic mutation that leaves the body unable to produce an enzyme; a protein that speeds up the rate at which chemical reactions take place within the body. The enzyme is necessary for nerve cells to metabolise fat, (allow for chemical reactions to take place within the cell) . The enzyme involved in TSD is known as hexosaminidase A. its absence allows a lipid called GM2 ganglioside to build up in the brain, destroying the nerve cells.

The location of the gene HEXA that causes the genetic disorder is 15q23-q24. Tay-Sachs is an autosomal recessive disorder. My......

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Title: Tay-Sachs
Approximate Word Count: 545
Approximate Pages: 3 (250 words per double-spaced page)

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1. Tay Sachs
   

   Tay Sachs. Abstract Tay-Sachs disease is a fatal inherited disease of the central
   nervous system. ... Death occurs by age 5. Who Is at Risk of Tay-Sachs Disease? ... ...

2. Tay Sachs Disease
   

   tay sachs disease. What is Tay-Sachs Disease? ... Infants with Tay-Sachs disease
   appear to develop normally for the first few months of life. ... ...

3. Tay Sachs Paper (With Outline)
   

   Tay Sachs paper (with outline). I. What is Tay-Sachs..? ... Tay-Sachs is recessive, and
   caused by the mutations in both of the allelles belonging to Chromosome 15. ... ...

4. What Is Tay-Sachs Disease
   

   ... Sachs Disease By Argenia J. Dikes Nov. 28, 2005 3rd hr Bibliography · http://www.
   ygyh.org/tay · www.ninds.nih.gov/health_and_medical/disorders/taysachs · www ... ...

5. Tay-Sachs
   

   tay-sachs. ... Children affected will die usually around the age of 5. What condition
   could possibly be so fatal and devastating? Tay-Sachs. ... ...